Recruiting NA INTERVENTIONAL 5-arm NCT05036538

Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients. (DESTRESS-SURG)

Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients. A Randomized Controlled Trial on Relaxation Interventions Via Virtual Reality and Binaural Beats.

Sponsor: Heart and Brain Research Group, Germany

Conditions Postoperative Cognitive Dysfunction Postoperative Delirium Preoperative Stress

Interventions Intervention with natural sounds administered via headphones Intervention with natural sounds and binaural beats administered via headphones Intervention with natural sounds and virtual reality administered via headphones and head mounted display Intervention with natural sounds, binaural beats and virtual reality administered via headphones and head mounted display

Updated 9 times since 2021 Last updated: Feb 13, 2026 Started: Jul 27, 2023 Primary completion: Aug 31, 2028 Completion: Nov 30, 2028

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Postoperative Cognitive Dysfunction and Postoperative Delirium and is currently actively recruiting participants. Heart and Brain Research Group, Germany leads this study, which shows 9 recorded versions since 2023 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

9 versions recorded

Feb 2026 — Present [monthly]

Recruiting NA

Status: Unknown → Recruiting
Jan 2026 — Feb 2026 [monthly]

Unknown NA

Status: Recruiting → Unknown
Sep 2024 — Jan 2026 [monthly]

Recruiting NA
Jul 2024 — Sep 2024 [monthly]

Recruiting NA
Sep 2023 — Jul 2024 [monthly]

Recruiting NA

Status: Not Yet Recruiting → Recruiting

▶ Show 4 earlier versions

Dec 2022 — Sep 2023 [monthly]

Not Yet Recruiting NA
Nov 2022 — Dec 2022 [monthly]

Not Yet Recruiting NA
Apr 2022 — Nov 2022 [monthly]

Not Yet Recruiting NA
Oct 2021 — Apr 2022 [monthly]

Not Yet Recruiting NA

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Heart and Brain Research Group, Germany

Data source: Heart and Brain Research Group, Germany

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Bad Nauheim, Germany