deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 3-arm NCT05037123

Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain (KALPAS)

Sponsor: NYU Langone Health

Conditions Chronic Postsurgical Pain
Interventions Continuous ketamine infusion Ketamine + Saline Placebo
Updated 11 times since 2021 Last updated: Jun 24, 2025 Started: Jan 4, 2022 Primary completion: May 28, 2025 Completion: Aug 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Chronic Postsurgical Pain and is currently ongoing. NYU Langone Health leads this study, which shows 11 recorded versions since 2022 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Oct 2021 – ~Apr 2022 · 6 months · monthly snapshotNot Yet Recruiting~Apr 2022 – ~May 2022 · 30 days · monthly snapshotRecruiting~May 2022 – ~Sep 2022 · 4 months · monthly snapshotRecruiting~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshotRecruiting~Nov 2022 – ~Sep 2023 · 10 months · monthly snapshotRecruiting~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~May 2025 · 8 months · monthly snapshotRecruiting~May 2025 – ~Jul 2025 · 2 months · monthly snapshotActive Not Recruiting~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshotActive Not Recruiting~Sep 2025 – present · 10 months · monthly snapshotActive Not Recruiting

Change History

11 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Jul 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  3. May 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  4. Sep 2024 — May 2025 [monthly]

    Recruiting PHASE3

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

▶ Show 6 earlier versions

  1. Sep 2023 — Jul 2024 [monthly]

    Recruiting PHASE3

  2. Nov 2022 — Sep 2023 [monthly]

    Recruiting PHASE3

  3. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  4. May 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  5. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  6. Oct 2021 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • NYU Langone Health
  • National Cancer Institute (NCI)
Data source: NYU Langone Health

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Birmingham, United States , Chestnut Hill, United States , Chicago, United States , Dallas, United States , Houston, United States , Little Rock, United States , New York, United States , Pittsburgh, United States , Rochester, United States , Seattle, United States and 2 more locations