deltatrials
Unknown PHASE2 INTERVENTIONAL 3-arm NCT05065021

Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitor

Re-VOLVE: A Phase II Clinical Trial in Women With Ovarian Cancer Progressing Post-PARP Inhibitor With Treatment Adapted to Real-time Assessment of Evolving Genomic Resistance

Sponsor: GlaxoSmithKline

Updated 8 times since 2021 Last updated: Jan 14, 2024 Started: Feb 23, 2023 Primary completion: Jun 6, 2025 Completion: Jun 6, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Fallopian Tube Cancer and High Grade Endometrioid Cancer, this trial is ongoing. The trial is conducted by GlaxoSmithKline and has accumulated 8 data snapshots since 2023. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Oct 2021 – ~Jun 2022 · 8 months · monthly snapshotNot Yet Recruiting~Jun 2022 – ~Apr 2023 · 10 months · monthly snapshotNot Yet Recruiting~Apr 2023 – ~Aug 2023 · 4 months · monthly snapshot~Aug 2023 – ~Feb 2024 · 6 months · monthly snapshotRecruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshotRecruiting~Feb 2026 – present · 7 months · monthly snapshotUnknown

Change History

8 versions recorded
  1. Feb 2026 — Present [monthly]

    Unknown PHASE2

    Status: RecruitingUnknown

  2. Sep 2024 — Feb 2026 [monthly]

    Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  4. Feb 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  5. Aug 2023 — Feb 2024 [monthly]

    Recruiting PHASE2

Show 3 earlier versions
  1. Apr 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  2. Jun 2022 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE2

  3. Oct 2021 — Jun 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
  • University Health Network, Toronto
Data source: University Health Network, Toronto

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations