deltatrials
Completed INTERVENTIONAL NCT05066672

Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NV-5138 in Adults With Treatment Resistant Depression

Sponsor: Navitor Pharmaceuticals, Inc.

Updated 7 times since 2021 Last updated: Apr 3, 2026 Started: Jan 18, 2022 Primary completion: Jan 21, 2025 Completion: Jan 21, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05066672, this observational or N/A phase trial focuses on Treatment Resistant Depression and remains completed. Sponsored by Navitor Pharmaceuticals, Inc., it has been updated 7 times since 2022, reflecting limited change activity. Mental health research at this phase helps define safety and dosing parameters for future study.

Study Description(click to expand)

The is a multicenter, randomized, double-blind, flexible- dose, placebo-controlled, parallel design of adjunctive NV-5138 in adults with TRD.

The is a multicenter, randomized, double-blind, flexible- dose, placebo-controlled, parallel design of adjunctive NV-5138 in adults with TRD.

Status Flow

~Nov 2021 – ~Apr 2022 · 5 months · monthly snapshotNot Yet Recruiting~Apr 2022 – ~Dec 2023 · 20 months · monthly snapshotRecruiting~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshotRecruiting~Jun 2025 – ~Apr 2026 · 11 months · monthly snapshotCompletedApr 18, 2026 – present · 3 months · daily API

Change History

7 versions recorded
  1. Apr 18, 2026 — Present [daily]

    Completed

    Phase: PHASE2None

  2. Jun 2025 — Apr 2026 [monthly]

    Completed PHASE2

    Status: RecruitingCompleted

  3. Sep 2024 — Jun 2025 [monthly]

    Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Dec 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

Show 2 earlier versions
  1. Apr 2022 — Dec 2023 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  2. Nov 2021 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

This study will evaluate the efficacy and safety of NV-5138 in adults with TRD

Contact Information

Sponsor contact:
  • Navitor Pharmaceuticals, Inc.
  • Supernus Pharmaceuticals, Inc.
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations