deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 3-arm NCT05077709

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

A Phase II Multi-Arm (Basket) Trial Investigating the Safety and Efficacy of IO102-IO103 in Combination With Pembrolizumab, as First-Line Treatment for Patients With Metastatic NSCLC, SCCHN, or Metastatic mUBC

Sponsor: Almac

Updated 13 times since 2021 Last updated: Jul 22, 2024 Started: Feb 14, 2022 Primary completion: Jan 4, 2024 Completion: Nov 30, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05077709, this PHASE2 trial focuses on Head and Neck Squamous Cell Carcinoma and Lung Cancer Non Small Cell and remains ongoing. Sponsored by Almac, it has been updated 13 times since 2022, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Nov 2021 – ~Apr 2022 · 5 months · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2023 · 6 months · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  4. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

  5. Jul 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

Show 8 earlier versions
  1. Jan 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

  2. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

  3. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

  4. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  5. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE2

  6. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  7. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  8. Nov 2021 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Almac
  • IO Biotech
  • Merck Sharp & Dohme LLC
  • NeoGenomics
  • Theradex
Data source: IO Biotech

For direct contact, visit the study record on ClinicalTrials.gov .