Completed NA INTERVENTIONAL 6-arm NCT05090150

The SMART ART Study

A Sequential Multiple Assignment Randomized Trial of Scalable Interventions for ART Delivery in South Africa: the SMART ART Study

Sponsor: Massachusetts General Hospital

Conditions ART HIV

Interventions Best clinic practices Best clinic practices + conditional lottery incentives Home delivery of ART Smart Lockers (Pele boxes)

Updated 7 times since 2021 Last updated: Jan 9, 2026 Started: Nov 2, 2021 Primary completion: Jul 3, 2025 Completion: Jul 3, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05090150, this NA trial focuses on ART and HIV and remains completed. Sponsored by Massachusetts General Hospital, it has been updated 7 times since 2021, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

Change History

7 versions recorded

Feb 2026 — Present [monthly]

Completed NA

Status: Recruiting → Completed
Sep 2024 — Feb 2026 [monthly]

Recruiting NA
Jul 2024 — Sep 2024 [monthly]

Recruiting NA
Mar 2024 — Jul 2024 [monthly]

Recruiting NA
Apr 2023 — Mar 2024 [monthly]

Recruiting NA

▶ Show 2 earlier versions

Dec 2021 — Apr 2023 [monthly]

Recruiting NA

Status: Not Yet Recruiting → Recruiting
Nov 2021 — Dec 2021 [monthly]

Not Yet Recruiting NA

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Massachusetts General Hospital
National Institute of Mental Health (NIMH)

Data source: Massachusetts General Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Sweetwaters, South Africa