deltatrials
Active Not Recruiting PHASE4 INTERVENTIONAL 2-arm NCT05096195

PRevEnting FracturEs in REnal Disease - 1 (PREFERRED-1)

Denosumab for the Prevention of Fragility Fractures in Hemodialysis: a Pilot Study for an Innovative, Randomized-controlled Trial, Embedded in Routine Care

Sponsor: Academic Medical Organization of Southwestern Ontario

Updated 11 times since 2021 Last updated: May 26, 2025 Started: Jun 11, 2022 Primary completion: Dec 31, 2025 Completion: Dec 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05096195, this PHASE4 trial focuses on Chronic Kidney Disease-Mineral and Bone Disorder and Dialysis; Complications and remains ongoing. Sponsored by Academic Medical Organization of Southwestern Ontario, it has been updated 11 times since 2022, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Nov 2021 – ~Jun 2022 · 7 months · monthly snapshotNot Yet Recruiting~Jun 2022 – ~Feb 2023 · 8 months · monthly snapshotNot Yet Recruiting~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshotRecruiting~Apr 2023 – ~Jul 2023 · 3 months · monthly snapshotRecruiting~Jul 2023 – ~Oct 2023 · 3 months · monthly snapshotRecruiting~Oct 2023 – ~Jun 2024 · 8 months · monthly snapshotRecruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotRecruiting~Oct 2024 – ~Jun 2025 · 8 months · monthly snapshotActive Not Recruiting~Jun 2025 – present · 15 months · monthly snapshotActive Not Recruiting

Change History

11 versions recorded
  1. Jun 2025 — Present [monthly]

    Active Not Recruiting PHASE4

  2. Oct 2024 — Jun 2025 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE4

  5. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE4

Show 6 earlier versions
  1. Oct 2023 — Jun 2024 [monthly]

    Recruiting PHASE4

  2. Jul 2023 — Oct 2023 [monthly]

    Recruiting PHASE4

  3. Apr 2023 — Jul 2023 [monthly]

    Recruiting PHASE4

  4. Feb 2023 — Apr 2023 [monthly]

    Recruiting PHASE4

    Status: Not Yet RecruitingRecruiting

  5. Jun 2022 — Feb 2023 [monthly]

    Not Yet Recruiting PHASE4

  6. Nov 2021 — Jun 2022 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Academic Medical Organization of Southwestern Ontario
  • ICES
  • The Kidney Foundation of Canada
  • Western University
  • Western University, Canada
Data source: Western University, Canada

For direct contact, visit the study record on ClinicalTrials.gov .