Recruiting NA INTERVENTIONAL 2-arm NCT05120635

Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

Sponsor: Duke University

Conditions Emotional Memory Fear GAD PTSD

Interventions Deep Brain Stimulation Virtual and augmented reality tasks

Updated 12 times since 2021 Last updated: Dec 11, 2025 Started: Oct 1, 2021 Primary completion: Jun 30, 2026 Completion: Jun 30, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Emotional Memory and Fear, this trial is actively recruiting participants. The trial is conducted by Duke University and has accumulated 12 data snapshots since 2021. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

12 versions recorded

Jan 2026 — Present [monthly]

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Oct 2025 — Jan 2026 [monthly]

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Aug 2025 — Oct 2025 [monthly]

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May 2025 — Aug 2025 [monthly]

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Apr 2025 — May 2025 [monthly]

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▶ Show 7 earlier versions

Sep 2024 — Apr 2025 [monthly]

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Jul 2024 — Sep 2024 [monthly]

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May 2024 — Jul 2024 [monthly]

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Jun 2023 — May 2024 [monthly]

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May 2022 — Jun 2023 [monthly]

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Mar 2022 — May 2022 [monthly]

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Dec 2021 — Mar 2022 [monthly]

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First recorded

Oct 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Duke University
National Institute of Mental Health (NIMH)
National Institutes of Health (NIH)
NeuroPace
VA Greater Los Angeles Healthcare System

Data source: Duke University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Durham, United States
• Los Angeles, United States