deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT05122650

A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)

A Phase 2b, 12-week, Double-blind, Placebo-controlled, Randomized, Parallel Group, Multicenter Study of the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor

Sponsor: Jazz Pharmaceuticals

Conditions Essential Tremor
Interventions JZP385 Placebo
Updated 28 times since 2021 Last updated: Jul 6, 2025 Started: Dec 6, 2021 Primary completion: May 30, 2024 Completion: May 30, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Essential Tremor and is currently completed. Jazz Pharmaceuticals leads this study, which shows 28 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Apr 2024 · 2 months · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

28 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Aug 2025 — Sep 2025 [monthly]

    Completed PHASE2

  3. Sep 2024 — Aug 2025 [monthly]

    Completed PHASE2

  4. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  5. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 23 earlier versions

  1. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  2. May 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Apr 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  4. Feb 2024 — Apr 2024 [monthly]

    Recruiting PHASE2

  5. Dec 2023 — Feb 2024 [monthly]

    Recruiting PHASE2

  6. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE2

  7. Sep 2023 — Nov 2023 [monthly]

    Recruiting PHASE2

  8. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE2

  9. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

  10. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

  11. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE2

  12. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE2

  13. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

  14. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE2

  15. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE2

  16. Sep 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

  17. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  18. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE2

  19. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  20. Mar 2022 — May 2022 [monthly]

    Recruiting PHASE2

  21. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE2

  22. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE2

  23. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Jazz Pharmaceuticals
Data source: Jazz Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Altamonte Springs, United States , Amherst, United States , Atlanta, United States , Atlantis, United States , Bad Homburg, Germany , Barakaldo, Spain , Barcelona, Spain , Beavercreek, United States , Bentonville, United States , Birmingham, United States and 48 more locations