Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT05127018

Higher Doses of Botulinum Toxin in the Treatment of Gummy Smile

Dose Higher Doses of Botulinum Toxin Show Better Intensity and Duration in the Treatment of Gummy Smile

Sponsor: Peking University

Conditions Botulinum Toxins, Type A Smiling

Interventions injection of Botulinum type A

Updated 5 times since 2021 Last updated: Apr 4, 2023 Started: Nov 20, 2019 Primary completion: Aug 20, 2020 Completion: Oct 20, 2021

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Botulinum Toxins, Type A and Smiling and is currently completed. Peking University leads this study, which shows 5 recorded versions since 2019 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

5 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
May 2023 — Jul 2024 [monthly]

Completed PHASE1_PHASE2

Phase: PHASE4 → PHASE1_PHASE2
Jan 2022 — May 2023 [monthly]

Completed PHASE4
Dec 2021 — Jan 2022 [monthly]

Completed PHASE4

First recorded

Nov 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Peking University

Data source: Peking University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Beijing, China