deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT05156229

A Phase 1/2a Study of CDK-003 in Patients With Cutaneous T-Cell Lymphoma (CTCL). (Part B)

A Phase 1/2a Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CDK-003 in Healthy Adult Participants and Intralesionally Administered CDK-003 in Patients With Cutaneous T-cell Lymphoma (CTCL)

Sponsor: Codiak BioSciences

Interventions CDK-003
Updated 5 times since 2022 Last updated: Aug 30, 2022 Started: Sep 6, 2021 Primary completion: Aug 24, 2022 Completion: Aug 24, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

PK/PD from two patients plus the healthy volunteer data confirmed the RP2D and manageable safety profile. Proceeding to Phase II did not require additional data from this Phase I Dose-Finding study.

Other terminated trials from Codiak BioSciences

More terminations from Codiak BioSciences

This PHASE1 trial investigates Cutaneous T-cell Lymphoma (CTCL) and is currently terminated or withdrawn. Codiak BioSciences leads this study, which shows 5 recorded versions since 2021 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2022 – ~May 2022 · 4 months · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

5 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Sep 2022 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: RecruitingTerminated

  4. May 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  5. Jan 2022 — May 2022 [monthly]

    Recruiting PHASE1

    First recorded

Sep 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Codiak BioSciences
Data source: Codiak BioSciences

For direct contact, visit the study record on ClinicalTrials.gov .