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Recruiting INTERVENTIONAL NCT05156398

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Rimegepant in Migraine Prevention in Children and Adolescents ≥ 6 to <18 Years of Age

Sponsor: Pfizer

Conditions Migraine
Updated 42 times since 2022 Last updated: Apr 15, 2026 Started: Feb 28, 2022 Primary completion: Nov 29, 2031 Completion: Nov 27, 2032
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on Migraine, this trial is actively recruiting participants. The trial is conducted by Pfizer and has accumulated 42 data snapshots since 2022. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Dec 2023 · 2 months · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Feb 2025 · 2 months · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Apr 2026 · 2 months · monthly snapshotApr 17, 2026 – present · 4 months · daily API

Change History

42 versions recorded
  1. Apr 17, 2026 — Present [daily]

    Recruiting

    Phase: PHASE3None

  2. Feb 2026 — Apr 2026 [monthly]

    Recruiting PHASE3

  3. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE3

  4. Dec 2025 — Jan 2026 [monthly]

    Recruiting PHASE3

  5. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE3

Show 37 earlier versions
  1. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE3

  2. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE3

  3. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  4. Jul 2025 — Aug 2025 [monthly]

    Recruiting PHASE3

  5. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE3

  6. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE3

  7. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE3

  8. Feb 2025 — Apr 2025 [monthly]

    Recruiting PHASE3

  9. Dec 2024 — Feb 2025 [monthly]

    Recruiting PHASE3

  10. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE3

  11. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  12. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  13. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  14. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  15. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE3

  16. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE3

  17. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE3

  18. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE3

  19. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE3

  20. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE3

  21. Oct 2023 — Dec 2023 [monthly]

    Recruiting PHASE3

  22. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE3

  23. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE3

  24. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  25. May 2023 — Jul 2023 [monthly]

    Recruiting PHASE3

  26. Mar 2023 — May 2023 [monthly]

    Recruiting PHASE3

  27. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

  28. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE3

  29. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  30. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  31. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  32. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  33. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  34. Apr 2022 — Jun 2022 [monthly]

    Recruiting PHASE3

  35. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  36. Feb 2022 — Mar 2022 [monthly]

    Not Yet Recruiting PHASE3

  37. Jan 2022 — Feb 2022 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

The purpose of this study is to compare the efficacy and safety of rimegepant to placebo as a preventative treatment for migraine in children and adolescents ≥ 6 to \<18 years with episodic migraine.

Contact Information

Sponsor contact:
  • Pfizer
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .