deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT05169944

Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors (PNOC025)

A Phase 1 Study of Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors

Sponsor: Gilead Sciences

Interventions Magrolimab
Updated 13 times since 2022 Last updated: Jul 8, 2025 Started: Apr 22, 2022 Primary completion: Sep 30, 2024 Completion: Sep 30, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05169944, this PHASE1 trial focuses on Brain Cancer and Brain Tumor Adult and remains completed. Sponsored by Gilead Sciences, it has been updated 13 times since 2022, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Nov 2022 · 5 months · monthly snapshot~Nov 2022 – ~Apr 2023 · 5 months · monthly snapshot~Apr 2023 – ~Oct 2023 · 6 months · monthly snapshot~Oct 2023 – ~Feb 2024 · 4 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Aug 2025 · 9 months · monthly snapshot~Aug 2025 – present · 13 months · monthly snapshot

Change History

13 versions recorded
  1. Aug 2025 — Present [monthly]

    Completed PHASE1

  2. Nov 2024 — Aug 2025 [monthly]

    Completed PHASE1

    Status: SuspendedCompleted

  3. Sep 2024 — Nov 2024 [monthly]

    Suspended PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Suspended PHASE1

  5. Mar 2024 — Jul 2024 [monthly]

    Suspended PHASE1

    Status: RecruitingSuspended

Show 8 earlier versions
  1. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE1

  2. Oct 2023 — Feb 2024 [monthly]

    Recruiting PHASE1

  3. Apr 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

  4. Nov 2022 — Apr 2023 [monthly]

    Recruiting PHASE1

  5. Jun 2022 — Nov 2022 [monthly]

    Recruiting PHASE1

  6. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  7. Apr 2022 — May 2022 [monthly]

    Not Yet Recruiting PHASE1

  8. Jan 2022 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gilead Sciences
  • University of California, San Francisco
Data source: University of California, San Francisco

For direct contact, visit the study record on ClinicalTrials.gov .