deltatrials
Active Not Recruiting NA INTERVENTIONAL 2-arm NCT05172960

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

Safety and Effectiveness of Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve

Sponsor: Edwards Lifesciences

Interventions SAPIEN X4 THV
Updated 18 times since 2022 Last updated: Aug 13, 2025 Started: Jun 20, 2022 Primary completion: Jul 22, 2025 Completion: Dec 31, 2034
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Aortic Stenosis, Severe and is currently ongoing. Edwards Lifesciences leads this study, which shows 18 recorded versions since 2022 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2022 – ~Jul 2022 · 6 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2023 · 6 months · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~May 2024 · 3 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Sep 2025 · 8 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

18 versions recorded
  1. Sep 2025 — Present [monthly]

    Active Not Recruiting NA

  2. Jan 2025 — Sep 2025 [monthly]

    Active Not Recruiting NA

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Jan 2025 [monthly]

    Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  5. May 2024 — Jul 2024 [monthly]

    Recruiting NA

Show 13 earlier versions
  1. Feb 2024 — May 2024 [monthly]

    Recruiting NA

  2. Jan 2024 — Feb 2024 [monthly]

    Recruiting NA

  3. Dec 2023 — Jan 2024 [monthly]

    Recruiting NA

  4. Nov 2023 — Dec 2023 [monthly]

    Recruiting NA

  5. Oct 2023 — Nov 2023 [monthly]

    Recruiting NA

  6. Sep 2023 — Oct 2023 [monthly]

    Recruiting NA

  7. Aug 2023 — Sep 2023 [monthly]

    Recruiting NA

  8. Jul 2023 — Aug 2023 [monthly]

    Recruiting NA

    Status: Active Not RecruitingRecruiting

  9. Jan 2023 — Jul 2023 [monthly]

    Active Not Recruiting NA

    Status: RecruitingActive Not Recruiting

  10. Dec 2022 — Jan 2023 [monthly]

    Recruiting NA

  11. Sep 2022 — Dec 2022 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  12. Jul 2022 — Sep 2022 [monthly]

    Not Yet Recruiting NA

    Status: WithheldNot Yet Recruiting · Phase: NoneNA

  13. Jan 2022 — Jul 2022 [monthly]

    Withheld

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Edwards Lifesciences
Data source: Edwards Lifesciences

For direct contact, visit the study record on ClinicalTrials.gov .