deltatrials
Terminated PHASE2 INTERVENTIONAL 3-arm NCT05182476

Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia (ERUDITE)

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Subjects With Cognitive Impairment Associated With Schizophrenia, Followed by Open-Label Treatment

Sponsor: Neurocrine Biosciences

Conditions Schizophrenia
Updated 15 times since 2022 Last updated: Jun 25, 2025 Started: Dec 7, 2021 Primary completion: Jun 28, 2024 Completion: Oct 14, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Failed to meet the primary endpoint

This PHASE2 trial investigates Schizophrenia and is currently terminated or withdrawn. Neurocrine Biosciences leads this study, which shows 15 recorded versions since 2021 — indicating substantial longitudinal coverage. This study adds to the longitudinal dataset for psychiatric treatment development.

Status Flow

~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Dec 2022 · 5 months · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~Aug 2023 · 6 months · monthly snapshot~Aug 2023 – ~May 2024 · 9 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Aug 2025 · 7 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

15 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Aug 2025 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jan 2025 — Aug 2025 [monthly]

    Terminated PHASE2

    Status: Active Not RecruitingTerminated

  4. Sep 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE2

  5. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

Show 10 earlier versions
  1. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE2

  2. May 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Aug 2023 — May 2024 [monthly]

    Recruiting PHASE2

  4. Feb 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

  5. Dec 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  6. Jul 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

  7. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE2

  8. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE2

  9. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE2

  10. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE2

    First recorded

Dec 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Neurocrine Biosciences
Data source: Neurocrine Biosciences

For direct contact, visit the study record on ClinicalTrials.gov .