deltatrials
Recruiting PHASE2 INTERVENTIONAL 1-arm NCT05209620

Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System Lymphoma

A Single Arm, Phase II Clinical Trial of Orelabrutinib Combined With Pemetrexed in the Treatment for Patients With Relapsed/Refractory Central Nervous System Lymphoma

Sponsor: Henan Cancer Hospital

Updated 6 times since 2022 Last updated: Apr 18, 2025 Started: Dec 21, 2021 Primary completion: Jun 30, 2025 Completion: Dec 21, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Central Nervous System Lymphoma and is currently actively recruiting participants. Henan Cancer Hospital leads this study, which shows 6 recorded versions since 2021 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshotNot Yet Recruiting~Mar 2022 – ~Jun 2023 · 15 months · monthly snapshotRecruiting~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~May 2025 · 8 months · monthly snapshotRecruiting~May 2025 – present · 16 months · monthly snapshotRecruiting

Change History

6 versions recorded
  1. May 2025 — Present [monthly]

    Recruiting PHASE2

  2. Sep 2024 — May 2025 [monthly]

    Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  4. Jun 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

  5. Mar 2022 — Jun 2023 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

Show 1 earlier version
  1. Feb 2022 — Mar 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Dec 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Henan Cancer Hospital
Data source: Henan Cancer Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations