deltatrials
Terminated PHASE1 INTERVENTIONAL 3-arm NCT05228015

Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects with Advanced Solid Tumors

A Phase 1, First-in-Human Study of IK-930, an Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects with Advanced Solid Tumors

Sponsor: Ikena Oncology

Updated 9 times since 2022 Last updated: Nov 14, 2024 Started: Jan 7, 2022 Primary completion: Aug 27, 2024 Completion: Sep 9, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor strategic reasons

Listed as NCT05228015, this PHASE1 trial focuses on Epithelioid Hemangioendothelioma (EHE) and Malignant Pleural Mesothelioma (MPM) and remains terminated or withdrawn. Sponsored by Ikena Oncology, it has been updated 9 times since 2022, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshotRecruiting~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshotRecruiting~Jul 2022 – ~Feb 2023 · 7 months · monthly snapshotRecruiting~Feb 2023 – ~Aug 2023 · 6 months · monthly snapshotRecruiting~Aug 2023 – ~May 2024 · 9 months · monthly snapshotRecruiting~May 2024 – ~Jul 2024 · 2 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotActive Not Recruiting~Dec 2024 – present · 19 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Dec 2024 — Present [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  2. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  5. Aug 2023 — May 2024 [monthly]

    Recruiting PHASE1

Show 4 earlier versions
  1. Feb 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  2. Jul 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  3. Apr 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

  4. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE1

    First recorded

Jan 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Ikena Oncology
Data source: Ikena Oncology

For direct contact, visit the study record on ClinicalTrials.gov .