deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT05237713

Efficacy and Safety of Canakinumab for the Treatment of Anemia in LR-MDS Patients

A Phase II, Single-Arm, Open-Label Study to Assess the Efficacy and Safety of Canakinumab for the Treatment of Anemia in Patients With IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes or MDS/MPN

Sponsor: Novartis Pharmaceuticals

Updated 10 times since 2022 Last updated: May 3, 2024 Started: Apr 26, 2022 Primary completion: Feb 29, 2024 Completion: Feb 29, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Slow recruitment. It is not considered likely that the CANFIRE trial will be able to reach the target number of patients. Clinical responders will be further treated within the trial (expected duration: 3 years after stop of enrollment).

A PHASE2 clinical study on Anemia and Myelodysplastic Syndromes, this trial is terminated or withdrawn. The trial is conducted by Novartis Pharmaceuticals and has accumulated 10 data snapshots since 2022. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshotNot Yet Recruiting~Apr 2022 – ~May 2022 · 30 days · monthly snapshotNot Yet Recruiting~May 2022 – ~Jun 2022 · 31 days · monthly snapshotNot Yet Recruiting~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshotRecruiting~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshotRecruiting~Dec 2022 – ~Sep 2023 · 9 months · monthly snapshotRecruiting~Sep 2023 – ~Jun 2024 · 9 months · monthly snapshotRecruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Jun 2024 — Jul 2024 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  4. Sep 2023 — Jun 2024 [monthly]

    Recruiting PHASE2

  5. Dec 2022 — Sep 2023 [monthly]

    Recruiting PHASE2

Show 5 earlier versions
  1. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

  2. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. May 2022 — Jun 2022 [monthly]

    Not Yet Recruiting PHASE2

  4. Apr 2022 — May 2022 [monthly]

    Not Yet Recruiting PHASE2

  5. Mar 2022 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
  • University of Leipzig
Data source: University of Leipzig

For direct contact, visit the study record on ClinicalTrials.gov .