deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT05242822

A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations

A Phase 1/1b, Open-label, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-tumor Activity of KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations

Sponsor: Kinnate Biopharma

Interventions KIN-3248
Updated 18 times since 2022 Last updated: May 5, 2025 Started: Mar 29, 2022 Primary completion: Oct 3, 2024 Completion: Oct 3, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Due to a change in the Sponsor's corporate strategy the study was terminated early by the Sponsor prior to enrollment into the dose expansion part of the study (Part B).

A PHASE1 clinical study on Intrahepatic Cholangiocarcinoma and Solid Tumor, Adult, this trial is terminated or withdrawn. The trial is conducted by Kinnate Biopharma and has accumulated 18 data snapshots since 2022. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Jan 2024 · 4 months · monthly snapshot~Jan 2024 – ~May 2024 · 4 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

18 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Jun 2025 — Sep 2025 [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  3. Sep 2024 — Jun 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  5. May 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

Show 13 earlier versions
  1. Jan 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  2. Sep 2023 — Jan 2024 [monthly]

    Recruiting PHASE1

  3. Jul 2023 — Sep 2023 [monthly]

    Recruiting PHASE1

  4. May 2023 — Jul 2023 [monthly]

    Recruiting PHASE1

  5. Mar 2023 — May 2023 [monthly]

    Recruiting PHASE1

  6. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE1

  7. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE1

  8. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE1

  9. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

  10. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  11. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE1

  12. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  13. Mar 2022 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kinnate Biopharma
Data source: Kinnate Biopharma

For direct contact, visit the study record on ClinicalTrials.gov .