deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT05261490

Study of Maplirpacept (PF-07901801) in Combination With PLD in Patients With Platinum-Resistant Ovarian Cancer

A Phase Ⅰ/Ⅱ Study of TTI-622 in Combination With Pegylated Liposomal Doxorubicin in Patients With Platinum-Resistant Ovarian Cancer

Sponsor: Pfizer

Updated 17 times since 2022 Last updated: Oct 31, 2024 Started: Aug 1, 2022 Primary completion: Oct 11, 2023 Completion: Feb 15, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

A business decision was made by Pfizer to terminate and remove the Phase 2 expansion of this study for administrative reasons. The reason for study termination is not due to any safety concerns or requests from regulatory authorities.

This PHASE1/PHASE2 trial investigates Epithelial Ovarian Cancer and Fallopian Tube Cancer and is currently terminated or withdrawn. Pfizer leads this study, which shows 17 recorded versions since 2022 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~Jun 2023 · 2 months · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~May 2024 · 4 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – present · 19 months · monthly snapshot

Change History

17 versions recorded
  1. Dec 2024 — Present [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE2PHASE1/PHASE2

  2. Nov 2024 — Dec 2024 [monthly]

    Terminated PHASE2

    Phase: PHASE1/PHASE2PHASE2

  3. Sep 2024 — Nov 2024 [monthly]

    Terminated PHASE1/PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  5. May 2024 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

    Status: Active Not RecruitingTerminated

Show 12 earlier versions
  1. Jan 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Dec 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Nov 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  4. Sep 2023 — Nov 2023 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jul 2023 — Sep 2023 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE1_PHASE2

    Phase: PHASE2PHASE1_PHASE2

  7. Apr 2023 — Jun 2023 [monthly]

    Recruiting PHASE2

  8. Feb 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

  9. Nov 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

    Phase: PHASE1_PHASE2PHASE2

  10. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE1_PHASE2

  11. May 2022 — Sep 2022 [monthly]

    Recruiting PHASE1_PHASE2

  12. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer
Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .