deltatrials
Terminated EARLY_PHASE1 INTERVENTIONAL 1-arm NCT05284032

A Pilot Trial Using Isatuximab to Overcome Platelet Transfusion Refractoriness in Human Leukocyte Antigen Allo-Immunized Patients (SuppCare 001)

A Pilot Trial Using Isatuximab to Overcome Platelet Transfusion Refractoriness in Human Leukocyte Antigen Allo-Immunized Patients

Sponsor: Firas El Chaer, MD

Interventions isatuximab 10 mg/kg
Updated 8 times since 2022 Last updated: Jul 29, 2024 Started: Nov 29, 2022 Primary completion: Jun 11, 2024 Completion: Jun 11, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Slow accrual

This EARLY_PHASE1 trial investigates Hematologic Malignancy and Platelet Refractoriness and is currently terminated or withdrawn. Firas El Chaer, MD leads this study, which shows 8 recorded versions since 2022 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshotNot Yet Recruiting~Jun 2022 – ~Dec 2022 · 6 months · monthly snapshotNot Yet Recruiting~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshotRecruiting~Feb 2023 – ~Sep 2023 · 7 months · monthly snapshotRecruiting~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotRecruiting~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotRecruiting~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated EARLY_PHASE1

  2. Aug 2024 — Sep 2024 [monthly]

    Terminated EARLY_PHASE1

    Status: RecruitingTerminated

  3. Jul 2024 — Aug 2024 [monthly]

    Recruiting EARLY_PHASE1

  4. Sep 2023 — Jul 2024 [monthly]

    Recruiting EARLY_PHASE1

  5. Feb 2023 — Sep 2023 [monthly]

    Recruiting EARLY_PHASE1

Show 3 earlier versions
  1. Dec 2022 — Feb 2023 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet RecruitingRecruiting

  2. Jun 2022 — Dec 2022 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  3. Apr 2022 — Jun 2022 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Firas El Chaer, MD
Data source: University of Virginia

For direct contact, visit the study record on ClinicalTrials.gov .