Completed PHASE3 INTERVENTIONAL 2-arm NCT05301634

Comparison Between Bilateral Infraorbital Block Versus Intranasal Bupivacaine in Transsphenoidal Pituitary Adenoma Resection

Comparison Between Hemodynamic Effect of Bilateral Infraorbital Block Versus Intranasal Application of Bupivacaine in Patients Undergoing Transsphenoidal Pituitary Adenoma Resection.A Comparative Randomized Controlled Study

Sponsor: Cairo University

Conditions Intraoperative Hypertension

Interventions infraorbital block topical intranasal bupivacaine

Updated 6 times since 2022 Last updated: Dec 23, 2025 Started: Apr 2, 2022 Primary completion: Jul 30, 2025 Completion: Dec 15, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Intraoperative Hypertension, this trial is completed. The trial is conducted by Cairo University and has accumulated 6 data snapshots since 2022. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

Change History

6 versions recorded

Jan 2026 — Present [monthly]

Completed PHASE3

Status: Unknown → Completed
Sep 2024 — Jan 2026 [monthly]

Unknown PHASE3
Jul 2024 — Sep 2024 [monthly]

Unknown PHASE3

Status: Unknown Status → Unknown
Jun 2024 — Jul 2024 [monthly]

Unknown Status PHASE3

Status: Recruiting → Unknown Status
Jun 2022 — Jun 2024 [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting

▶ Show 1 earlier version

Apr 2022 — Jun 2022 [monthly]

Not Yet Recruiting PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Cairo University

Data source: Cairo University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Cairo, Egypt