deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 3-arm NCT05311618

Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors

A Phase 1/1b Dose Escalation/Expansion Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors

Sponsor: Merck Sharp & Dohme LLC

Updated 8 times since 2022 Last updated: Mar 28, 2024 Started: May 11, 2022 Primary completion: Apr 30, 2025 Completion: Jun 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Bladder Urothelial Cancer and Breast Cancer, this trial is ongoing. The trial is conducted by Merck Sharp & Dohme LLC and has accumulated 8 data snapshots since 2022. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~May 2022 – ~Jun 2022 · 31 days · monthly snapshotNot Yet Recruiting~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshotRecruiting~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshotRecruiting~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshotRecruiting~Nov 2022 – ~May 2024 · 18 months · monthly snapshotRecruiting~May 2024 – ~Jul 2024 · 2 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – present · 23 months · monthly snapshotActive Not Recruiting

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  3. May 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Nov 2022 — May 2024 [monthly]

    Recruiting PHASE1

  5. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE1

Show 3 earlier versions
  1. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  2. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  3. May 2022 — Jun 2022 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
  • NGM Biopharmaceuticals, Inc
Data source: NGM Biopharmaceuticals, Inc

For direct contact, visit the study record on ClinicalTrials.gov .