deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT05385705

A Study of Allogenic Natural Killer Cells in Combination With Trastuzumab and Pertuzumab in Adult Patients With Refractory Metastatic Her2 Positive Breast Cancer. NK-ACT-BC_2020

A Phase Ib Study With a Safety lead-in Cohort and Expansion Phase, of the Safety, Tolerability, Biological Effect, and Efficacy of Allogenic Natural Killer Cells in Combination With Trastuzumab and Pertuzumab in Adult Patients With Refractory Metastatic Her2 Positive Breast Cancer

Sponsor: Banc de Sang i Teixits

Updated 6 times since 2022 Last updated: Sep 16, 2025 Started: May 11, 2022 Primary completion: Jul 11, 2024 Completion: Jul 11, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Slow recruitment rate

This PHASE1 trial investigates Breast Neoplasms and is currently terminated or withdrawn. Banc de Sang i Teixits leads this study, which shows 6 recorded versions since 2022 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshotRecruiting~Jul 2022 – ~May 2024 · 22 months · monthly snapshotRecruiting~May 2024 – ~Jul 2024 · 2 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshotRecruiting~Oct 2025 – present · 8 months · monthly snapshotTerminated

Change History

6 versions recorded
  1. Oct 2025 — Present [monthly]

    Terminated PHASE1

    Status: RecruitingTerminated

  2. Sep 2024 — Oct 2025 [monthly]

    Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  4. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  5. Jul 2022 — May 2024 [monthly]

    Recruiting PHASE1

Show 1 earlier version
  1. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

    First recorded

May 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Banc de Sang i Teixits
  • Clinica Universidad de Navarra, Universidad de Navarra
  • Hospital del Mar
  • Puerta de Hierro University Hospital
  • Vall d'Hebron Institute of Oncology
Data source: Vall d'Hebron Institute of Oncology

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations