deltatrials
Recruiting PHASE1 INTERVENTIONAL 1-arm NCT05400603

Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma (Aflac-NBL-2002)

A Phase I Study of Allogeneic Ex Vivo Expanded Gamma Delta (γδ) T Cells in Combination With Dinutuximab, Temozolomide, Irinotecan, and Zoledronate in Children With Refractory/ Relapsed, or Progressive Neuroblastoma or Refractory/ Relapsed Osteosarcoma

Sponsor: Emory University

Updated 13 times since 2022 Last updated: Dec 19, 2025 Started: Nov 6, 2023 Primary completion: Dec 31, 2026 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Neuroblastoma and Refractory Neuroblastoma and is currently actively recruiting participants. Emory University leads this study, which shows 13 recorded versions since 2023 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jul 2022 – ~Nov 2022 · 4 months · monthly snapshot~Nov 2022 – ~Mar 2023 · 4 months · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Oct 2023 · 5 months · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshot~Oct 2025 – ~Jan 2026 · 3 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

13 versions recorded
  1. Jan 2026 — Present [monthly]

    Recruiting PHASE1

  2. Oct 2025 — Jan 2026 [monthly]

    Recruiting PHASE1

  3. Sep 2024 — Oct 2025 [monthly]

    Recruiting PHASE1

  4. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  5. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

Show 8 earlier versions
  1. Dec 2023 — Jul 2024 [monthly]

    Recruiting PHASE1

  2. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  3. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  4. May 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

  5. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  6. Mar 2023 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE1

  7. Nov 2022 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE1

  8. Jul 2022 — Nov 2022 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Emory University
Data source: Emory University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations