deltatrials
Recruiting NA INTERVENTIONAL 5-arm NCT05420064

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Digital Technology to Enhance Access to and Effectiveness of Cancer Genetic Counseling: Effective Familial OutReach Via Tele-genetics (EfFORT) Trial & Supporting Test Result Interpretation and Variant Education (STRIVE) Trial

Sponsor: Memorial Sloan Kettering Cancer Center

Conditions APC Gene Mutation ATM Gene Mutation BARD1 Gene Mutation BMPR1A Gene Mutation BRCA1 Mutation BRCA2 Mutation BRIP1 Gene Mutation CDKN2A Mutation CHEK2 Gene Mutation EPCAM Gene Mutation GREM1 MLH1 Gene Mutation MSH2 Gene Mutation MSH6 Gene Mutation PALB2 Gene Mutation PMS2 Gene Mutation POLD1 Gene Mutation POLE Gene Mutation PTEN Gene Mutation RAD51C Gene Mutation RAD51D Gene Mutation SMAD4
Interventions Intervention Arm At-risk Relative/ARR Contacts MyGene Portal Standard of Care
Updated 15 times since 2022 Last updated: Nov 10, 2025 Started: Dec 1, 2022 Primary completion: May 31, 2026 Completion: Nov 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates APC Gene Mutation and ATM Gene Mutation and is currently actively recruiting participants. Memorial Sloan Kettering Cancer Center leads this study, which shows 15 recorded versions since 2022 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Apr 2023 · 4 months · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Oct 2023 · 5 months · monthly snapshot~Oct 2023 – ~Jan 2024 · 3 months · monthly snapshot~Jan 2024 – ~May 2024 · 4 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Apr 2025 · 3 months · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Dec 2025 · 7 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

15 versions recorded

  1. Dec 2025 — Present [monthly]

    Recruiting NA

  2. May 2025 — Dec 2025 [monthly]

    Recruiting NA

  3. Apr 2025 — May 2025 [monthly]

    Recruiting NA

  4. Jan 2025 — Apr 2025 [monthly]

    Recruiting NA

  5. Nov 2024 — Jan 2025 [monthly]

    Recruiting NA

▶ Show 10 earlier versions

  1. Sep 2024 — Nov 2024 [monthly]

    Recruiting NA

  2. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  3. May 2024 — Jul 2024 [monthly]

    Recruiting NA

  4. Jan 2024 — May 2024 [monthly]

    Recruiting NA

  5. Oct 2023 — Jan 2024 [monthly]

    Recruiting NA

  6. May 2023 — Oct 2023 [monthly]

    Recruiting NA

    Phase: None → NA

  7. Apr 2023 — May 2023 [monthly]

    Recruiting

  8. Dec 2022 — Apr 2023 [monthly]

    Recruiting

  9. Sep 2022 — Dec 2022 [monthly]

    Recruiting

  10. Jul 2022 — Sep 2022 [monthly]

    Recruiting

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Memorial Sloan Kettering Cancer Center
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations