deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT05438602

A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System

AN INTERVENTIONAL EFFICACY AND SAFETY, PHASE 2, RANDOMIZED, DOUBLE-BLIND, 3-ARM STUDY TO INVESTIGATE NIRMATRELVIR/RITONAVIR IN NONHOSPITALIZED PARTICIPANTS AT LEAST 12 YEARS OF AGE WITH SYMPTOMATIC COVID-19 WHO ARE IMMUNOCOMPROMISED

Sponsor: Pfizer

Conditions COVID-19
Updated 19 times since 2022 Last updated: Sep 16, 2024 Started: Aug 3, 2022 Primary completion: Jul 17, 2023 Completion: Nov 13, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on COVID-19, this trial is completed. The trial is conducted by Pfizer and has accumulated 19 data snapshots since 2022. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Sep 2025 · 11 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

19 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Oct 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Sep 2024 — Oct 2024 [monthly]

    Completed PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  5. Feb 2024 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

Show 14 earlier versions
  1. Dec 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Nov 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Oct 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Sep 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE2

  5. Aug 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  6. Jul 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  7. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

  8. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE2

  9. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE2

  10. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

  11. Jan 2023 — Mar 2023 [monthly]

    Recruiting PHASE2

  12. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

  13. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  14. Jul 2022 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer
Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .