deltatrials
Recruiting PHASE2 INTERVENTIONAL 2-arm NCT05456256

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma (HARMONIC)

Phase II Trial of LP-300 in Combination With Carboplatin and Pemetrexed in Never Smoker Patients With Relapsed Advanced Primary Adenocarcinoma of the Lung After Treatment With Tyrosine Kinase Inhibitors (The HARMONIC Study)

Sponsor: Lantern Pharma Inc.

Updated 18 times since 2022 Last updated: Nov 17, 2025 Started: Mar 1, 2023 Primary completion: Dec 31, 2025 Completion: Jun 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Adenocarcinoma of Lung and Carcinoma, Non-Small-Cell Lung and is currently actively recruiting participants. Lantern Pharma Inc. leads this study, which shows 18 recorded versions since 2023 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Jul 2023 · 4 months · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Dec 2023 · 3 months · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Jun 2024 · 4 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Aug 2025 · 7 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – present · 8 months · monthly snapshot

Change History

18 versions recorded
  1. Dec 2025 — Present [monthly]

    Recruiting PHASE2

  2. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE2

  3. Sep 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  4. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  5. Jan 2025 — Aug 2025 [monthly]

    Recruiting PHASE2

Show 13 earlier versions
  1. Nov 2024 — Jan 2025 [monthly]

    Recruiting PHASE2

  2. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE2

  3. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  4. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

  5. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  6. Feb 2024 — Jun 2024 [monthly]

    Recruiting PHASE2

  7. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE2

  8. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE2

  9. Sep 2023 — Dec 2023 [monthly]

    Recruiting PHASE2

  10. Jul 2023 — Sep 2023 [monthly]

    Recruiting PHASE2

  11. Mar 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

  12. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE2

  13. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Lantern Pharma Inc.
Data source: Lantern Pharma Inc.

For direct contact, visit the study record on ClinicalTrials.gov .