deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT05458102

Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels

A Phase 1, Open-label, Multicohort Study to Evaluate the Impact of Inhibitors and Inducers of Cytochrome P450 Enzyme (CYP)3A and/or P-glycoprotein (P-gp) on the Pharmacokinetics (PK) of Vesatolimod (VES) in Virologically Suppressed Adults With HIV-1 on Antiretroviral Therapy (ART)

Sponsor: Gilead Sciences

Updated 10 times since 2022 Last updated: Oct 11, 2024 Started: Aug 19, 2022 Primary completion: May 1, 2023 Completion: May 1, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor's decision to change the clinical development plan of this molecule. This decision is not based on efficacy or safety concerns.

A PHASE1 clinical study on Human Immunodeficiency Virus Type 1 (HIV-1) Infection, this trial is terminated or withdrawn. The trial is conducted by Gilead Sciences and has accumulated 10 data snapshots since 2022. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshotRecruiting~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshotRecruiting~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshotRecruiting~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshotRecruiting~Apr 2023 – ~Jun 2023 · 2 months · monthly snapshotRecruiting~Jun 2023 – ~Dec 2023 · 6 months · monthly snapshotActive Not Recruiting~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshotTerminated~Jan 2025 – present · 18 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Jan 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Jan 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Dec 2023 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  5. Jun 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

Show 5 earlier versions
  1. Apr 2023 — Jun 2023 [monthly]

    Recruiting PHASE1

  2. Feb 2023 — Apr 2023 [monthly]

    Recruiting PHASE1

  3. Dec 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  4. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

  5. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE1

    First recorded

Aug 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gilead Sciences
Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .