Active Not Recruiting PHASE2 INTERVENTIONAL 2-arm NCT05463367

Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure

Sponsor: National Institutes of Health (NIH)

Conditions Back Injuries Back Pain Chronic Low-back Pain Chronic Pain Narcotic Use Opioid Dependence Opioid Use Opioid-use Disorder Pain, Back Pain, Chronic Pain;Back Low;Chronic

Interventions Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet Naproxen 500 Mg Opioids

Updated 5 times since 2022 Last updated: Nov 22, 2024 Started: Jan 1, 2021 Primary completion: Jun 1, 2025 Completion: Jun 1, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Back Injuries and Back Pain, this trial is ongoing. The trial is conducted by National Institutes of Health (NIH) and has accumulated 5 data snapshots since 2021. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

5 versions recorded

Dec 2024 — Present [monthly]

Active Not Recruiting PHASE2

Status: Recruiting → Active Not Recruiting
Sep 2024 — Dec 2024 [monthly]

Recruiting PHASE2
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE2
Jul 2023 — Jul 2024 [monthly]

Recruiting PHASE2
Sep 2022 — Jul 2023 [monthly]

Recruiting PHASE2

First recorded

Jan 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Institutes of Health (NIH)
Northwestern University
Shirley Ryan AbilityLab

Data source: Northwestern University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Chicago, United States