deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 4-arm NCT05469178

A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 Gene

Phase 1b/2a Safety and Tolerability Study of Bemcentinib With Pembrolizumab/Carboplatin/Pemetrexed in Subjects With Untreated Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) Without/With a STK11 Mutation

Sponsor: BerGenBio ASA

Updated 9 times since 2022 Last updated: Oct 2, 2025 Started: Mar 3, 2023 Primary completion: Apr 3, 2025 Completion: Apr 3, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Lack of efficacy

A PHASE1/PHASE2 clinical study on Carcinoma, Non-Small-Cell Lung, this trial is terminated or withdrawn. The trial is conducted by BerGenBio ASA and has accumulated 9 data snapshots since 2023. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Sep 2022 – ~May 2023 · 8 months · monthly snapshotNot Yet Recruiting~May 2023 – ~Nov 2023 · 6 months · monthly snapshotRecruiting~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotRecruiting~Feb 2025 – ~Jun 2025 · 4 months · monthly snapshotRecruiting~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Nov 2025 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Sep 2025 — Nov 2025 [monthly]

    Terminated PHASE1/PHASE2

  3. Jun 2025 — Sep 2025 [monthly]

    Terminated PHASE1/PHASE2

    Status: RecruitingTerminated

  4. Feb 2025 — Jun 2025 [monthly]

    Recruiting PHASE1/PHASE2

  5. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE1/PHASE2

Show 4 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  2. Nov 2023 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  3. May 2023 — Nov 2023 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  4. Sep 2022 — May 2023 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • BerGenBio ASA
Data source: BerGenBio ASA

For direct contact, visit the study record on ClinicalTrials.gov .