deltatrials
Recruiting PHASE1 INTERVENTIONAL 7-arm NCT05547321

Efficacy and Safety Study of OMTX705, Monotherapy and Anti-PD-1-combined, in Subjects With Advanced Solid Tumors.

Phase 1 Dose-escalation Trial of OMTX705, an Anti-fibroblast Activation Protein Antibody-drug Conjugate, as Single Agent and in Combination With Anti-PD-1 in Patients With Advanced Solid Tumors

Sponsor: Alcura Health España SA

Updated 6 times since 2022 Last updated: Nov 20, 2025 Started: Oct 20, 2022 Primary completion: Dec 31, 2027 Completion: Dec 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Advanced Solid Tumor and is currently actively recruiting participants. Alcura Health España SA leads this study, which shows 6 recorded versions since 2022 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshotNot Yet Recruiting~Mar 2023 – ~Mar 2024 · 12 months · monthly snapshotRecruiting~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2025 · 15 months · monthly snapshotRecruiting~Dec 2025 – present · 7 months · monthly snapshotRecruiting

Change History

6 versions recorded
  1. Dec 2025 — Present [monthly]

    Recruiting PHASE1

  2. Sep 2024 — Dec 2025 [monthly]

    Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  4. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  5. Mar 2023 — Mar 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

Show 1 earlier version
  1. Sep 2022 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alcura Health España SA
  • Anapharm Bioanalytics
  • Biotrial
  • CTI Laboratory Services Spain
  • Centro de Investigación del Cáncer Universidad de Salamanca
  • Certara
  • Clinigen, Inc.
  • Evidenze
  • HistoOne
  • Oncomatryx Biopharma S.L.
  • Opthimapharm
  • TFS Health Science
Data source: Oncomatryx Biopharma S.L.

For direct contact, visit the study record on ClinicalTrials.gov .