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Terminated PHASE2 INTERVENTIONAL 2-arm NCT05567835

A Study of Total Neoadjuvant Chemotherapy With FLOT VS Standard Perioperative FLOT in Patients With Gastric or GEJ Cancer (TOGAR)

A Randomized, Open Labeled Phase II Pilot Study of Total Neoadjuvant Chemotherapy With FLOT ( FLOT-TNT) VS Standard Perioperative FLOT ( FLOTPOP) in Patients With Gastric or GEJ Cancer, and Assessment of CTDNA as Correlative Biological Response

Sponsor: Baylor College of Medicine

Updated 11 times since 2022 Last updated: Feb 4, 2026 Started: Mar 6, 2024 Primary completion: Feb 20, 2025 Completion: Feb 20, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Since activation, 3 subjects were enrolled but were ineligible for randomization to a treatment arm because of a positive diagnostic laparoscopy result. Given the repeat inability to enroll and randomize an eligible subject; accrual was halted.

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This PHASE2 trial investigates Gastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma and is currently terminated or withdrawn. Baylor College of Medicine leads this study, which shows 11 recorded versions since 2024 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshotNot Yet Recruiting~Dec 2022 – ~Apr 2023 · 4 months · monthly snapshotNot Yet Recruiting~Apr 2023 – ~Sep 2023 · 5 months · monthly snapshotNot Yet Recruiting~Sep 2023 – ~Feb 2024 · 5 months · monthly snapshotNot Yet Recruiting~Feb 2024 – ~Apr 2024 · 2 months · monthly snapshotNot Yet Recruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshotRecruiting~Jan 2025 – ~May 2025 · 4 months · monthly snapshotRecruiting~May 2025 – ~Feb 2026 · 9 months · monthly snapshotTerminated~Feb 2026 – present · 3 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE2

  2. May 2025 — Feb 2026 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  3. Jan 2025 — May 2025 [monthly]

    Recruiting PHASE2

  4. Sep 2024 — Jan 2025 [monthly]

    Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

Show 6 earlier versions
  1. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  2. Feb 2024 — Apr 2024 [monthly]

    Not Yet Recruiting PHASE2

  3. Sep 2023 — Feb 2024 [monthly]

    Not Yet Recruiting PHASE2

  4. Apr 2023 — Sep 2023 [monthly]

    Not Yet Recruiting PHASE2

  5. Dec 2022 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE2

  6. Nov 2022 — Dec 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Baylor College of Medicine
Data source: Baylor College of Medicine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations