deltatrials
Enrolling By Invitation PHASE4 INTERVENTIONAL 2-arm NCT05579626

Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus (PROVE-DM)

Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus in Prediabetic Patients With Atherosclerotic Cardiovascular Disease

Sponsor: Seung-Whan Lee, M.D., Ph.D.

Updated 13 times since 2022 Last updated: Jan 6, 2026 Started: Mar 14, 2023 Primary completion: Dec 31, 2030 Completion: Dec 31, 2030
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on ASCVD and Pre Diabetes, this trial is ongoing. The trial is conducted by Seung-Whan Lee, M.D., Ph.D. and has accumulated 13 data snapshots since 2023. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Nov 2022 – ~Apr 2023 · 5 months · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Jan 2024 · 6 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Dec 2024 · 2 months · monthly snapshot~Dec 2024 – ~Feb 2025 · 2 months · monthly snapshot~Feb 2025 – ~Jul 2025 · 5 months · monthly snapshot~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

13 versions recorded
  1. Feb 2026 — Present [monthly]

    Enrolling By Invitation PHASE4

    Status: RecruitingEnrolling By Invitation

  2. Sep 2025 — Feb 2026 [monthly]

    Recruiting PHASE4

  3. Jul 2025 — Sep 2025 [monthly]

    Recruiting PHASE4

    Phase: NAPHASE4

  4. Feb 2025 — Jul 2025 [monthly]

    Recruiting NA

  5. Dec 2024 — Feb 2025 [monthly]

    Recruiting NA

Show 8 earlier versions
  1. Oct 2024 — Dec 2024 [monthly]

    Recruiting NA

  2. Sep 2024 — Oct 2024 [monthly]

    Recruiting NA

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  4. Jan 2024 — Jul 2024 [monthly]

    Recruiting NA

  5. Jul 2023 — Jan 2024 [monthly]

    Recruiting NA

  6. May 2023 — Jul 2023 [monthly]

    Recruiting NA

  7. Apr 2023 — May 2023 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  8. Nov 2022 — Apr 2023 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Seung-Whan Lee, M.D., Ph.D.
  • Yuhan Corporation
Data source: Asan Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .