deltatrials
Terminated PHASE4 INTERVENTIONAL 2-arm NCT05590923

Steroid-sparing Therapy (Olanzapine) Versus Dexamethasone-based Therapy for Chemotherapy-induced Nausea and Vomiting

The Efficacy of Steroid-Sparing Anti-Emetic Therapy in Patients Treated With High or Moderate Emetogenic Chemotherapy; Single Center Non-Inferiority Open Label Randomized Controlled Trial

Sponsor: The Guthrie Clinic

Updated 8 times since 2022 Last updated: Oct 30, 2025 Started: Dec 7, 2022 Primary completion: Jul 8, 2025 Completion: Jul 8, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Study stopped due to lower than expected accrual.

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This PHASE4 trial investigates Chemotherapy-induced Nausea and Vomiting and is currently terminated or withdrawn. The Guthrie Clinic leads this study, which shows 8 recorded versions since 2022 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshotNot Yet Recruiting~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshotRecruiting~Mar 2023 – ~Mar 2024 · 12 months · monthly snapshotRecruiting~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotRecruiting~Feb 2025 – ~Nov 2025 · 9 months · monthly snapshotRecruiting~Nov 2025 – present · 8 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Nov 2025 — Present [monthly]

    Terminated PHASE4

    Status: RecruitingTerminated

  2. Feb 2025 — Nov 2025 [monthly]

    Recruiting PHASE4

  3. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE4

  5. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE4

Show 3 earlier versions
  1. Mar 2023 — Mar 2024 [monthly]

    Recruiting PHASE4

  2. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE4

    Status: Not Yet RecruitingRecruiting

  3. Nov 2022 — Feb 2023 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • The Guthrie Clinic
Data source: The Guthrie Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations