Exploring the Mechanism of Primary Resistance to Third-generation EGFR-TKIs as First-line Treatment in EGFR-positive Advanced NSCLC (PRECISE Study) (PRECISE)
A Multicenter Clinical Study to Explore the Mechanism of Primary Resistance to Third-generation EGFR-TKIs as First-line Treatment in EGFR-positive Advanced NSCLC (PRECISE Study)
Sponsor: Changsha Central Hospital
This observational or N/A phase trial investigates Circulating Tumor DNA and EGFR Gene Mutation and is currently actively recruiting participants. Changsha Central Hospital leads this study, which shows 10 recorded versions since 2021 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.
Status Flow
Change History
10 versions recorded-
Sep 2025 — Present [monthly]
Recruiting
-
Aug 2025 — Sep 2025 [monthly]
Recruiting
-
Jun 2025 — Aug 2025 [monthly]
Recruiting
-
May 2025 — Jun 2025 [monthly]
Recruiting
-
Dec 2024 — May 2025 [monthly]
Recruiting
▶ Show 5 earlier versions
-
Sep 2024 — Dec 2024 [monthly]
Recruiting
-
Jul 2024 — Sep 2024 [monthly]
Recruiting
-
Sep 2023 — Jul 2024 [monthly]
Recruiting
-
Apr 2023 — Sep 2023 [monthly]
Recruiting
-
Nov 2022 — Apr 2023 [monthly]
Recruiting
First recorded
Sep 2021
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Changsha Central Hospital
- Changsha County first People's Hospital
- China-Japan Friendship Hospital
- First Affiliated Hospital of Guangxi Medical University
- First Affiliated Hospital of Kunming Medical University
- First Hospital of Changsha
- First People's Hospital of Chenzhou
- Fudan University
- Guiyang Public Health Treatment Center
- Hengyang Central Hospital
- Huaihua first people's Hospital
- Hunan Academy of Traditional Chinese Medicine Affiliated Hospital
- Hunan Cancer Hospital
- Hunan Provincial People's Hospital
- Hunan Provincial Straight Hospital of Traditional Chinese Medicine
- Hunan University of Traditional Chinese Medicine
- Liuyang Hospital of traditional Chinese Medicine
- Loudi Central Hospital
- People's Hospital of Zhangjiajie
- Renmin Hospital of Wuhan University
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Second People's Hospital Of Huaihua
- Second People's Hospital of Hunan
- Second Xiangya Hospital of Central South University
- Shanghai Chest Hospital
- Shaoyang Central Hospital
- The Affiliated Bethune Hospital of Shanxi Medical University
- The First Affiliated Hospital of Nanchang University
- The First Affiliated Hospital of University of South China
- The First Affiliated Hospital of Xiamen University
- The First People's Hospital of Changde City
- The First People's Hospital of Xiangtan
- The Third Hospital of Changsha
- The Third Xiangya Hospital of Central South University
- The first people's hospital of Guiyang
- Tongji Hospital
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- University of South China Affiliated Nanhua Hospital
- West China Hospital
- Xiangtan Central Hospital
- Xiangxi Autonomous Prefecture People's Hospital
- Xiangya Changde Hospital
- Xiangya Hospital of Central South University
- Yiyang Central Hospital
- Yongzhou Central Hospital
- Yueyang Central Hospital
- ZhuZhou Central Hospital
- Zhuzhou Second Hospital
For direct contact, visit the study record on ClinicalTrials.gov .