deltatrials
Recruiting PHASE2 INTERVENTIONAL 2-arm NCT05599347

Pre-treatment With Azithromycin to Reduce Immunogenicity to to Anti-TNF Agents in Patients With Crohn's Disease (AZITRATIM)

Pre-treatment With Azithromycin to Reduce Immunogenicity to Anti-Tumor Necrosis Factor-α Agents in Patients With Crohn's Disease

Sponsor: Rambam Health Care Campus

Conditions Biological Substance; Adverse Effect Crohn's Disease Relapse
Interventions Azithromycin Pill Placebo
Updated 6 times since 2022 Last updated: Apr 2, 2025 Started: Apr 24, 2023 Primary completion: Dec 31, 2025 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Biological Substance; Adverse Effect and Crohn's Disease Relapse and is currently actively recruiting participants. Rambam Health Care Campus leads this study, which shows 6 recorded versions since 2023 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Nov 2022 – ~Dec 2023 · 13 months · monthly snapshotNot Yet Recruiting~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~May 2025 · 8 months · monthly snapshotRecruiting~May 2025 – ~Sep 2025 · 4 months · monthly snapshotRecruiting~Sep 2025 – present · 10 months · monthly snapshotRecruiting

Change History

6 versions recorded

  1. Sep 2025 — Present [monthly]

    Recruiting PHASE2

  2. May 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  3. Sep 2024 — May 2025 [monthly]

    Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Dec 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

▶ Show 1 earlier version

  1. Nov 2022 — Dec 2023 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Rambam Health Care Campus
Data source: Rambam Health Care Campus

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations