deltatrials
Terminated INTERVENTIONAL NCT05605119

First in Human, Dose Escalation, Dose Expansion Study of AUR105 (SURYA-1)

A Phase 1, Open Label, Dose Escalation, Dose Expansion, Multicenter, First in Human (FIH) Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of Oral AUR105 in Patients With Relapsed Advanced Malignancies (SURYA-1)

Sponsor: Aurigene Discovery Technologies Limited

Interventions AUR105
Updated 6 times since 2022 Last updated: Apr 15, 2026 Started: Nov 30, 2022 Primary completion: Mar 1, 2024 Completion: Mar 1, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Patient recruitment problems.

This observational or N/A phase trial investigates Hodgkin Lymphoma and Non-hodgkin Lymphoma and is currently terminated or withdrawn. Aurigene Discovery Technologies Limited leads this study, which shows 6 recorded versions since 2022 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Study Description(click to expand)

This is a Phase I, Open label First in Human Study in adult patients with relapsed advanced malignancies. The study will have two parts. Dose escalation part and Dose expansion part

This is a Phase I, Open label First in Human Study in adult patients with relapsed advanced malignancies.

The study will have two parts. Dose escalation part and Dose expansion part

Status Flow

~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2023 – ~Feb 2024 · 13 months · monthly snapshotRecruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Apr 2026 · 20 months · monthly snapshotRecruitingApr 18, 2026 – present · 3 months · daily APITerminated

Change History

6 versions recorded
  1. Apr 18, 2026 — Present [daily]

    Terminated

    Status: RecruitingTerminated · Phase: PHASE1None

  2. Sep 2024 — Apr 2026 [monthly]

    Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  4. Feb 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  5. Jan 2023 — Feb 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

Show 1 earlier version
  1. Dec 2022 — Jan 2023 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Nov 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

This is a multi-center, open-label, First in Human, Phase 1 study of AUR 105 in adult patients with advanced malignancies. The study will have two parts: a Dose Escalation Part and Dose Expansion Part.

Contact Information

Sponsor contact:
  • Aurigene Discovery Technologies Limited
Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .