deltatrials
Terminated NA INTERVENTIONAL 1-arm NCT05605587

Leflunomide Treatment for MEN1 Patients - the LUMEN1 Trial (LUMEN1)

Sponsor: University Hospital, Basel, Switzerland

Interventions Leflunomide 20 mg
Updated 7 times since 2022 Last updated: Jan 23, 2026 Started: May 2, 2023 Primary completion: Jan 13, 2026 Completion: Jan 13, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was prematurely terminated due to significant difficulties in recruiting participants, arising from the extremely rare nature of the targeted gene mutation.

This NA trial investigates MEN1 Gene Mutation and is currently terminated or withdrawn. University Hospital, Basel, Switzerland leads this study, which shows 7 recorded versions since 2023 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Dec 2022 – ~Jul 2023 · 7 months · monthly snapshotNot Yet Recruiting~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotRecruiting~Feb 2025 – ~Dec 2025 · 10 months · monthly snapshotRecruiting~Dec 2025 – ~Feb 2026 · 2 months · monthly snapshot~Feb 2026 – present · 7 months · monthly snapshotTerminated

Change History

7 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated NA

    Status: Active Not RecruitingTerminated

  2. Dec 2025 — Feb 2026 [monthly]

    Active Not Recruiting NA

    Status: RecruitingActive Not Recruiting

  3. Feb 2025 — Dec 2025 [monthly]

    Recruiting NA

  4. Sep 2024 — Feb 2025 [monthly]

    Recruiting NA

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

Show 2 earlier versions
  1. Jul 2023 — Jul 2024 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  2. Dec 2022 — Jul 2023 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University Hospital, Basel, Switzerland
Data source: University Hospital, Basel, Switzerland

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations