deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT05626634

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

A Phase 2, Multicenter, Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy Who Completed Study LP352-201 and Are Candidates for Continuous Treatment for Up to 52 Weeks

Sponsor: Longboard Pharmaceuticals

Interventions LP352, bexicaserin
Updated 15 times since 2022 Last updated: Dec 2, 2025 Started: Nov 8, 2022 Primary completion: Dec 20, 2024 Completion: Dec 20, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05626634, this PHASE2 trial focuses on Developmental and Epileptic Encephalopathy and Dravet Syndrome and remains completed. Sponsored by Longboard Pharmaceuticals, it has been updated 15 times since 2022, reflecting substantial change activity. Mental health research at this phase helps define safety and dosing parameters for future study.

Status Flow

~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~Aug 2023 · 4 months · monthly snapshot~Aug 2023 – ~Oct 2023 · 2 months · monthly snapshot~Oct 2023 – ~Dec 2023 · 2 months · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Jun 2024 · 5 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

15 versions recorded
  1. Jan 2026 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Jan 2026 [monthly]

    Completed PHASE2

  3. Feb 2025 — Sep 2025 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  4. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE2

Show 10 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Jan 2024 — Jun 2024 [monthly]

    Recruiting PHASE2

  4. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE2

  5. Oct 2023 — Dec 2023 [monthly]

    Recruiting PHASE2

  6. Aug 2023 — Oct 2023 [monthly]

    Recruiting PHASE2

  7. Apr 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

  8. Feb 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

  9. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE2

  10. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

    First recorded

Nov 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Longboard Pharmaceuticals
Data source: Longboard Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .