deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT05669755

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels (REDEFINE 3)

The Cardiovascular Safety and Efficacy of Cagrilintide 2.4 mg s.c. in Combination With Semaglutide 2.4 mg s.c. (CagriSema 2.4 mg/2.4 mg s.c.) Once-weekly in Participants With Established Cardiovascular Disease

Sponsor: Novo Nordisk A/S

Updated 29 times since 2023 Last updated: Mar 10, 2026 Started: Mar 1, 2023 Primary completion: Sep 1, 2027 Completion: Oct 13, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Cardiovascular Disease, this trial is ongoing. The trial is conducted by Novo Nordisk A/S and has accumulated 29 data snapshots since 2023. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Oct 2023 · 5 months · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Aug 2025 · 3 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Mar 2026 · 59 days · monthly snapshot~Mar 2026 – present · 4 months · monthly snapshot

Change History

29 versions recorded
  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Jan 2026 — Mar 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Dec 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

  4. Nov 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Sep 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE3

Show 24 earlier versions
  1. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  2. May 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Apr 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Feb 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  6. Dec 2024 — Jan 2025 [monthly]

    Recruiting PHASE3

  7. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE3

  8. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE3

  9. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  10. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  11. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE3

  12. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  13. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE3

  14. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE3

  15. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE3

  16. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE3

  17. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE3

  18. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE3

  19. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE3

  20. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE3

  21. May 2023 — Oct 2023 [monthly]

    Recruiting PHASE3

  22. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  23. Mar 2023 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE3

  24. Feb 2023 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novo Nordisk A/S
Data source: Novo Nordisk A/S

For direct contact, visit the study record on ClinicalTrials.gov .