Completed NA INTERVENTIONAL 2-arm NCT05679596

Exogenous Ketosis During Bed Rest in Older Adults (KBR)

Ketone Bodies as Therapeutic Agents to Reduce the Harmful Effects of Bed Rest on Muscle Mass and Metabolic Health in Older Adults

Sponsor: Canadian Institutes of Health Research (CIHR)

Conditions Cognitive Function Functional Capacity Insulin Sensitivity Mitochondrial Function Muscle Atrophy Muscle Protein Synthesis Muscle Strength Physical Inactivity

Interventions carbohydrate-fat placebo (fructose, corn and canola oil 50:50 ratio) ketone monoester (R)-3-hydroxybutyl (R)-3- hydroxybutyrate

Updated 6 times since 2023 Last updated: Feb 6, 2024 Started: Feb 27, 2023 Primary completion: Nov 15, 2023 Completion: Nov 15, 2023

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05679596, this NA trial focuses on Cognitive Function and Functional Capacity and remains completed. Sponsored by Canadian Institutes of Health Research (CIHR), it has been updated 6 times since 2023, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

6 versions recorded

Sep 2025 — Present [monthly]

Completed NA
Sep 2024 — Sep 2025 [monthly]

Completed NA
Jul 2024 — Sep 2024 [monthly]

Completed NA
Mar 2024 — Jul 2024 [monthly]

Completed NA

Status: Recruiting → Completed
Mar 2023 — Mar 2024 [monthly]

Recruiting NA

▶ Show 1 earlier version

Feb 2023 — Mar 2023 [monthly]

Recruiting NA

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Canadian Institutes of Health Research (CIHR)
McGill University

Data source: McGill University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Montreal, Canada