deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT05696080

Safety and Immunogenicity of V116 in Adults With Increased Risk for Pneumococcal Disease (V116-008) (STRIDE-8)

A Phase 3, Randomized, Double-blind, Active Comparator-controlled Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 in Pneumococcal Vaccine-naïve Adults 18 to 64 Years of Age With Increased Risk for Pneumococcal Disease.

Sponsor: Merck Sharp & Dohme LLC

Updated 15 times since 2023 Last updated: Feb 10, 2026 Started: Feb 13, 2023 Primary completion: Feb 16, 2024 Completion: Feb 16, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Pneumococcal Infection, this trial is completed. The trial is conducted by Merck Sharp & Dohme LLC and has accumulated 15 data snapshots since 2023. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Mar 2024 · 6 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – ~Mar 2026 · 6 months · monthly snapshot~Mar 2026 – present · 4 months · monthly snapshot

Change History

15 versions recorded
  1. Mar 2026 — Present [monthly]

    Completed PHASE3

  2. Sep 2025 — Mar 2026 [monthly]

    Completed PHASE3

  3. Mar 2025 — Sep 2025 [monthly]

    Completed PHASE3

  4. Dec 2024 — Mar 2025 [monthly]

    Completed PHASE3

  5. Sep 2024 — Dec 2024 [monthly]

    Completed PHASE3

Show 10 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  2. Mar 2024 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  3. Sep 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  4. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE3

  5. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  6. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE3

  7. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE3

  8. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

  9. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  10. Feb 2023 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
Data source: Merck Sharp & Dohme LLC

For direct contact, visit the study record on ClinicalTrials.gov .