deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT05699603

Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients

Phase IIA, Single-Arm, Open- Label, Clinical Trial of Calcipotriene Plus 5-fluorouracil Immunotherapy for Skin Cancer Prevention in Organ Transplant Recipients

Sponsor: National Cancer Institute (NCI)

Updated 17 times since 2023 Last updated: Sep 23, 2025 Started: Jul 2, 2024 Primary completion: Feb 1, 2027 Completion: Feb 1, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05699603, this PHASE2 trial focuses on Actinic Keratosis and remains ongoing. Sponsored by National Cancer Institute (NCI), it has been updated 17 times since 2024, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~May 2023 · 2 months · monthly snapshot~May 2023 – ~Nov 2023 · 6 months · monthly snapshot~Nov 2023 – ~Feb 2024 · 3 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Sep 2025 · 8 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

17 versions recorded
  1. Oct 2025 — Present [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE2

  3. Jan 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  4. Nov 2024 — Jan 2025 [monthly]

    Recruiting PHASE2

  5. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE2

Show 12 earlier versions
  1. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

  2. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  3. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

  4. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  5. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Apr 2024 — May 2024 [monthly]

    Not Yet Recruiting PHASE2

  7. Mar 2024 — Apr 2024 [monthly]

    Not Yet Recruiting PHASE2

  8. Feb 2024 — Mar 2024 [monthly]

    Not Yet Recruiting PHASE2

  9. Nov 2023 — Feb 2024 [monthly]

    Not Yet Recruiting PHASE2

  10. May 2023 — Nov 2023 [monthly]

    Not Yet Recruiting PHASE2

  11. Mar 2023 — May 2023 [monthly]

    Not Yet Recruiting PHASE2

  12. Feb 2023 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • University of Arizona
Data source: University of Arizona

For direct contact, visit the study record on ClinicalTrials.gov .