deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 8-arm NCT05704049

A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma (IZALCO)

A Randomized, Phase 2, Open Label Study Evaluating Subcutaneous Administration of Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma (RRMM)

Sponsor: Sanofi

Updated 22 times since 2023 Last updated: Dec 26, 2025 Started: Apr 5, 2023 Primary completion: Dec 22, 2025 Completion: May 12, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05704049, this PHASE2 trial focuses on Relapsed/Refractory Multiple Myeloma and remains ongoing. Sponsored by Sanofi, it has been updated 22 times since 2023, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Jan 2024 · 2 months · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~May 2024 · 3 months · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Dec 2024 · 2 months · monthly snapshot~Dec 2024 – ~Jul 2025 · 7 months · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – ~Jan 2026 · 2 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

22 versions recorded
  1. Jan 2026 — Present [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Nov 2025 — Jan 2026 [monthly]

    Recruiting PHASE2

  3. Sep 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  4. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  5. Jul 2025 — Aug 2025 [monthly]

    Recruiting PHASE2

    Status: Active Not RecruitingRecruiting

Show 17 earlier versions
  1. Dec 2024 — Jul 2025 [monthly]

    Active Not Recruiting PHASE2

  2. Oct 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  6. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE2

  7. Feb 2024 — May 2024 [monthly]

    Recruiting PHASE2

  8. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE2

  9. Nov 2023 — Jan 2024 [monthly]

    Recruiting PHASE2

  10. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE2

  11. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE2

  12. Jul 2023 — Sep 2023 [monthly]

    Recruiting PHASE2

  13. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE2

  14. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE2

  15. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  16. Mar 2023 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE2

  17. Feb 2023 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sanofi
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .