Unknown PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT05721872

Efficacy, Tolerability and Safety of Intravenous D-VC With ATO in Patients With Advanced/Metastatic Colorectal Cancer

An Exploratory Phase I/II Single-center Clinical Trial of the Efficacy, Tolerability and Safety of Intravenous D-isoascorbic Acid With Arsenic Trioxide in Patients With Advanced/Metastatic Colorectal Cancer Who Have Exhausted Standard Therapy

Sponsor: National Laboratory Astana

Conditions Colorectal Cancer Metastatic Colorectal Cancer

Interventions D-isoascorbic Acid (D-VC) With Arsenic Trioxide (ATO) FOLFOX/FOLFIRI regimen

Updated 4 times since 2023 Last updated: Feb 8, 2023 Started: Feb 15, 2023 Primary completion: Aug 31, 2023 Completion: Nov 30, 2023

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05721872, this PHASE1/PHASE2 trial focuses on Colorectal Cancer and Metastatic Colorectal Cancer and remains ongoing. Sponsored by National Laboratory Astana, it has been updated 4 times since 2023, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

4 versions recorded

Mar 2025 — Present [monthly]

Unknown PHASE1/PHASE2

Status: Recruiting → Unknown
Sep 2024 — Mar 2025 [monthly]

Recruiting PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
Mar 2023 — Jul 2024 [monthly]

Recruiting PHASE1_PHASE2

First recorded

Feb 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Laboratory Astana
Nazarbayev University

Data source: Nazarbayev University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Almaty, Kazakhstan