Recruiting NA INTERVENTIONAL 4-arm NCT05761756

Oxygen Toxicity: Mechanisms in Humans

Applied Physiology of Oxygen Toxicity: Mechanisms in Humans

Sponsor: Duke University

Conditions Hypercapnia Oxygen Toxicity Seizures

Interventions Caffeine Carbon Dioxide Methylphenidate Sleep Deprivation

Updated 7 times since 2023 Last updated: Oct 21, 2025 Started: Nov 28, 2023 Primary completion: Aug 31, 2026 Completion: Aug 31, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Hypercapnia and Oxygen Toxicity, this trial is actively recruiting participants. The trial is conducted by Duke University and has accumulated 7 data snapshots since 2023. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

7 versions recorded

Nov 2025 — Present [monthly]

Recruiting NA
Apr 2025 — Nov 2025 [monthly]

Recruiting NA
Sep 2024 — Apr 2025 [monthly]

Recruiting NA
Jul 2024 — Sep 2024 [monthly]

Recruiting NA
Feb 2024 — Jul 2024 [monthly]

Recruiting NA

Status: Not Yet Recruiting → Recruiting

▶ Show 2 earlier versions

Dec 2023 — Feb 2024 [monthly]

Not Yet Recruiting NA
Apr 2023 — Dec 2023 [monthly]

Not Yet Recruiting NA

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Duke University

Data source: Duke University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Durham, United States