deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT05763576

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection

A Phase I Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection

Sponsor: Hoffmann-La Roche

Conditions Chronic Hepatitis B
Interventions Nucleos(t)ide analogue (NUC) treatment Placebo RO7565020
Updated 25 times since 2023 Last updated: Jan 20, 2026 Started: Apr 28, 2023 Primary completion: Dec 23, 2024 Completion: Dec 23, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The Sponsor decided to discontinue the development of RO7565020 and as a result the BP44118 study was terminated.

Other terminated trials from Hoffmann-La Roche

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Other Chronic Hepatitis B trials with similar outcome

Browse all Chronic Hepatitis B trials

This PHASE1 trial investigates Chronic Hepatitis B and is currently terminated or withdrawn. Hoffmann-La Roche leads this study, which shows 25 recorded versions since 2023 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 7 months · monthly snapshot

Change History

25 versions recorded

  1. Feb 2026 — Present [monthly]

    Terminated PHASE1

  2. Sep 2025 — Feb 2026 [monthly]

    Terminated PHASE1

  3. Feb 2025 — Sep 2025 [monthly]

    Terminated PHASE1

    Status: Recruiting → Terminated

  4. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE1

  5. Dec 2024 — Jan 2025 [monthly]

    Recruiting PHASE1

▶ Show 20 earlier versions

  1. Nov 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

  2. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE1

  3. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE1

  4. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  5. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  6. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  7. May 2024 — Jun 2024 [monthly]

    Recruiting PHASE1

  8. Apr 2024 — May 2024 [monthly]

    Recruiting PHASE1

  9. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE1

  10. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE1

  11. Jan 2024 — Feb 2024 [monthly]

    Recruiting PHASE1

  12. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE1

  13. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  14. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  15. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

  16. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE1

  17. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  18. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  19. May 2023 — Jun 2023 [monthly]

    Not Yet Recruiting PHASE1

  20. Apr 2023 — May 2023 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hoffmann-La Roche
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations