deltatrials
Recruiting PHASE1 INTERVENTIONAL 5-arm NCT05822544

Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes

A Phase 1/1b Study of Single and Multiple Ascending Doses of TLC 6740 in Healthy Subjects, Including Evaluation of Food Effect and Potential Drug-Drug Interactions, and Preliminary Safety and Efficacy in Subjects With Obesity, With or Without Diabetes

Sponsor: OrsoBio, Inc

Updated 12 times since 2023 Last updated: Dec 10, 2025 Started: Apr 22, 2023 Primary completion: Feb 28, 2026 Completion: Jun 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Healthy Subjects and Obesity and is currently actively recruiting participants. OrsoBio, Inc leads this study, which shows 12 recorded versions since 2023 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Dec 2023 · 6 months · monthly snapshotRecruiting~Dec 2023 – ~Apr 2024 · 4 months · monthly snapshotRecruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshotRecruiting~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshotRecruiting~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshotRecruiting~Jan 2026 – present · 6 months · monthly snapshotRecruiting

Change History

12 versions recorded
  1. Jan 2026 — Present [monthly]

    Recruiting PHASE1

  2. Sep 2025 — Jan 2026 [monthly]

    Recruiting PHASE1

  3. Jun 2025 — Sep 2025 [monthly]

    Recruiting PHASE1

  4. Mar 2025 — Jun 2025 [monthly]

    Recruiting PHASE1

  5. Dec 2024 — Mar 2025 [monthly]

    Recruiting PHASE1

Show 7 earlier versions
  1. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

  2. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  3. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  4. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  5. Dec 2023 — Apr 2024 [monthly]

    Recruiting PHASE1

  6. Jun 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  7. May 2023 — Jun 2023 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Apr 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • OrsoBio, Inc
Data source: OrsoBio, Inc

For direct contact, visit the study record on ClinicalTrials.gov .