Completed NA INTERVENTIONAL 2-arm NCT05842096

Subclinical Hypothyroidism and Chronic Inflammation in PCOS

The Influence of Subclinical Hypothyroidism on Chronic Inflammation Activity in Women With Different PCOS Phenotypes

Sponsor: Jagiellonian University

Conditions Hypothalamic-Pituitary-Gonadal Axis Dysfunction PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries Subclinical hypothyroïdism

Interventions Assessment of the impact of imbalance between anti- and pro-inflammatory factors in women with different PCOS and HPOD phenotypes on ovarian reserve indices Evaluation of the impact of subclinical hypothyroidism, with present/ absent antithyroid antibodies, on the balance between anti- and pro-inflammatory factors in women in both study arms Measurement and comparison of leucocytosis and concentrations of CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha in both study arms

Updated 8 times since 2023 Last updated: Apr 13, 2025 Started: Jan 1, 2024 Primary completion: Dec 30, 2024 Completion: Dec 30, 2024

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Hypothalamic-Pituitary-Gonadal Axis Dysfunction and PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, this trial is completed. The trial is conducted by Jagiellonian University and has accumulated 8 data snapshots since 2024. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed NA
May 2025 — Sep 2025 [monthly]

Completed NA

Status: Recruiting → Completed
Sep 2024 — May 2025 [monthly]

Recruiting NA
Aug 2024 — Sep 2024 [monthly]

Recruiting NA
Jul 2024 — Aug 2024 [monthly]

Recruiting NA

▶ Show 3 earlier versions

Mar 2024 — Jul 2024 [monthly]

Recruiting NA

Status: Not Yet Recruiting → Recruiting
Dec 2023 — Mar 2024 [monthly]

Not Yet Recruiting NA
Jun 2023 — Dec 2023 [monthly]

Not Yet Recruiting NA

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Jagiellonian University

Data source: Jagiellonian University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Krakow, Poland